Research Fellow in Mathematical Biology AFHEA/MHFA

School of Mathematical Sciences
Faculty of Science

About Me

I was awarded an MMathPhys in Applied Mathematics and Physics from the National University of Technology in Athens (Greece) before completing my Msc in Applied Mathematical Sciences with Biological and Ecological Modelling at Heriot-Watt University in Edinburgh, Scotland. During my studies, I worked on a broad range of topics in the areas of mathematical modelling, mathematical ecology, mathematical biology and medicine, dynamical systems, applied linear algebra, numerical analysis, regression analysis, linear models and designs, computer science along with their applications in physics and engineering.

In late 2012, I joined the University of Dundee and The James Hutton Institute to undertake a PhD in mathematical modelling of plant root systems funded by the European project EURoot.

After completing my PhD, I joined the School of Mathematical Sciences at the University of Nottingham in order to work on a Wellcome Trust-funded Collaborative Award entitled "Integrative Transport Phenomena in Chemokine Gradient Establishment" under the supervision of Dr. Bindi Brook in collaboration with Prof. James Moore at the Imperial College London and Prof. Robert Nibbs at the University of Glasgow. This research programme will lead to a deeper understanding of critical immunological processes that contribute to protection from infection, facilitate responses to vaccination and drive pathology in a broad spectrum of diseases. The implications in health and disease are therefore substantial and this study could aid the development of new immunoengineered therapies involving chemokine gradient manipulation.

For more information, please visit my webpage at the official website of the School of Mathematical Sciences at University of Nottingham as well as my LinkedIn and Twitter account.

My Research

Current Research

I am currently working on a Wellcome Trust-funded Collaborative Award entitled "Integrative Transport Phenomena in Chemokine Gradient Establishment" under the supervision of Dr. Bindi Brook in collaboration with Prof. James Moore at the Imperial College London and Prof. Robert Nibbs at the University of Glasgow. The principal goal of the project is to develop a comprehensive quantitative knowledge base of chemokine gradient formation and regulation using integrated experimental and modelling approaches. Chemokines are secreted chemoattractants that orchestrate the migration and positioning of leukocytes, and are indispensable components of all protective and pathogenic immune and inflammatory responses. A combination of diffusion, advection, binding kinetics and cellular uptake result in the generation of spatial chemokine gradients that govern leukocyte migration. If chemokine gradients are not appropriately tuned, leukocytes fail to respond and immune responses are compromised. This multidisciplinary project will provide unprecedented insight into this complex, dynamic and critically important process with a potential impact on vaccination and on the treatment of diseases with key immune cell contributions, such as allergy, autoimmunity, cardiovascular disease and cancer.

Past Research

In the past, I worked on the development and application of novel mathematical and computational methods in modelling of neurons as well as plant root systems. Innovative mathematical techniques in numerical simulation, model parameterisation and model sensitivity analysis were used to calibrate root growth density-based models on various genotypes in a range of reference environmental conditions. Results from this work on PDE modelling, numerical analysis, optimisation, application of PDEs to image analysis, image analysis pipelines, computer programming and plant image analysis software aimed to uncover key biological factors and plant traits that can be targeted by breeding.

Areas of research and teaching interest

Mathematical modelling, mathematical ecology, mathematical biology and medicine, dynamical systems, applied linear algebra, numerical analysis, regression analysis, linear models and designs, computer science along with their applications in physics and engineering. PDE/SDE modelling, numerical analysis, optimisation, application of PDEs to image analysis, image analysis pipelines, computer programming

My Teaching

I am an Associate Fellow of the Higher Education Academy and a Mental Health First aider (MHFA England). I am actively involved in teaching, student support and development at the University of Nottingham as well as the student mentoring programme at Heriot-Watt University in Edinburgh, Scotland. I have been responsible for the supervision of undergraduate students through their course projects and also mentored final year undergraduate Engineering students. I have assisted the preparation and delivery of undergraduate Mathematics lectures, seminars, tutorials and computer lab workshops.

I am really interested in different approaches to teaching Mathematics as well as in public engagement events about science and interdisciplinary research in Mathematics aimed at students and to the public.
For more information, please visit my LinkedIn and Twitter account.